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3 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
7 signs/symptoms
Dedifferentiated liposarcoma
Denys-Drash syndrome

CDK4 WT1
HMGA2
MDM2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
MDM2
(0.63)
WT1



Citations in the biomedical literature:


Dedifferentiated liposarcoma
CDK4 HMGA2 MDM2
Denys-Drash syndrome
WT1



Dedifferentiated liposarcoma
Denys-Drash syndrome

Synonym(s):
- DDLS

Synonym(s):
- Drash syndrome
- Wilms tumor and pseudohermaphroditism

Classification (Orphanet):
- Rare oncologic disease
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare endocrine disease
- Rare genetic disease
- Rare gynecologic or obstetric disease
- Rare oncologic disease
- Rare renal disease
- Rare urogenital disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Diseases of the genitourinary system -

Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: sporadic
Epidemiological data:
(no data available)

External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
1 MeSH reference: D030321

Denys-Drash syndrome

Very frequent
- Male pseudohermaphrodism / lack of virilisation
- Nephroblastoma / Wilms tumor
- Nephrotic syndrome
- Proteinuria
- Renal disease / nephropathy

Frequent
- Chronic arterial hypertension

Occasional
- Mixed gonadal dysgenesis


Dedifferentiated liposarcoma

(no data available)